Mohamed A. Abdelrahim
Department of Neurology, Faculty of medicine, University of Khartoum, Khartoum, Sudan
Title: Cosmetic effects of Anti-Epileptic Drugs among adult Sudanese epilepsy patients, Omdurman.
Biography
Biography: Mohamed A. Abdelrahim
Abstract
The study was performed on Sudanese epilepsy patients attending Daoud charity neurological clinic from June to September 2014. Data were collected using standardized set of questionnaires. Five main variables were used: (1) Cosmetic effects proile; (2) Morisky Medication Adherence Scale (MMAS-8); (3) WHO Quality of Life Brief-26; (4) socio-demographic data, and (5) clinical Epilepsy related data. Also, a senior neurologist assessed the cosmetic effects through clinical examination of the patients. Results: There were 42 patients (31% females); mean age 34.1±10.4 years. Hair loss was the most commonly reported cosmetic effect by female patients (75%) who were taking sodium valproate. (26.2%) of patients had weight gain and none of them thought weight gain is an adverse effect. Neither quality of life score, nor Adherence score were correlated with any of the cosmetic effects of AEDs (P>0.05). A significant positive correlation was found between the duration from the last attack and the quality of life score (P=0.03). The Gum overgrowth was correlated with the Hirsutism and Acne (P<0.05). Also the Skin Rash was correlated with the weight loss and Acne (P<0.05).